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Detection of Mycoplasma genitalium using a wireless magnetoelastic immunosensor

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成果类型:
期刊论文
作者:
He, Bo;Liao, Lifu*;Xiao, Xilin;Gao, Shuqin;Wu, Yimou
通讯作者:
Liao, Lifu
作者机构:
[Gao, Shuqin; Xiao, Xilin; Liao, Lifu; He, Bo] Univ S China, Coll Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.
[He, Bo] Univ S China, Coll Publ Hlth, Hengyang 421001, Hunan, Peoples R China.
[Xiao, Xilin] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China.
[Wu, Yimou] Univ S China, Inst Pathogen Biol, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Liao, Lifu] U
Univ S China, Coll Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.
语种:
英文
关键词:
Immunosensor;Magnetoelastic;Mycoplasma genitalium;Wireless
期刊:
Analytical Biochemistry
ISSN:
0003-2697
年:
2011
卷:
408
期:
1
页码:
1-4
基金类别:
The authors thank the National Natural Science Foundation of China ( 20877038 and 10975069 ), the Science Foundation of Hunan Provincial Public Health Department ( B2006-103 ), and the Scientific Foundation of Hunan Provincial Education Department ( 09C850 ) for financial support. The authors also thank Qingyun Cai (Hunan University) for help with the wireless magnetoelastic sensing device developed by Craig A. Grimes and coworkers (Pennsylvania State University) and Hannah E. Ihms (Department of Chemistry, University of Illinois) for critical reading of the manuscript.
机构署名:
本校为第一且通讯机构
院系归属:
化学化工学院
医学院
公共卫生学院
摘要:
A wireless immunosensor for the detection of Mycoplasma genitalium was fabricated by immobilizing polyclonal antibody onto the surface of a magnetostrictive strip. In response to a time-varying magnetic field, the immunosensor longitudinally vibrates at a resonance frequency, emitting magnetic flux that can be remotely detected by a pickup coil. No physical connections between the immunosensor and the detection system are required, facilitating wireless aseptic operation. The binding of M. genitalium to the immunosensor surface resulted in a de...

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