期刊论文

Dosimetric advantages of postoperative radiotherapy in flattening filter-free mode for left-sided breast cancer

中文

中国医学物理学杂志

1005-202X

2021

38

03

281-286

10.3969/j.issn.1005-202X.2021.03.003

浙江省重点科技研发计划（2019C03003）； 浙江省医药卫生科技计划（2020KY472）；

本校为第一机构

目的:比较左侧乳腺癌全切术后无均整器(FFF)与均整器(FF)模式下容积旋转调强放疗(VMAT)计划剂量学特点,分析无均整器模式下剂量学优势。方法:随机选取2019~2020年左侧乳腺癌全切术后的患者10例,分别用两种模式对同一患者的计划靶区(PTV)给予相同的处方剂量50 Gy,在RayStation计划系统上设计FFF和FF的VMAT计划,在满足临床要求的情况下,比较两组剂量学特点、机器总跳数、出束总时间。结果:FFF模式靶区PTV的D_(98%)低于FF模式(P=0.007),D_(95%)、 D_(2%)、CI、HI两者比较差异均无统计学意义(P>0.05);FFF模式在患侧肺、全肺、心脏、脊髓以及冠状动脉前降支保护上明显优于FF模式(P0.05);FFF模式的机器...

Objective To compare the dosimetric characteristics of volumetric modulated arc therapy(VMAT)plan in flattening filter(FF)mode and flattening filterⅢfree(FFF)mode,and to analyze the dosimetric advantages of FFF-VMAT. Methods Ten patients with left-sided breast cancer after total resection from 2019 to 2020 were randomly selected. The same prescription dose of 50 Gy was given to the planning target volume(PTV)of the same patient by two modes separately,and two kinds of plans,namely FFF-VMAT plan and FF-VMAT plan,were designed on RayStation plan...