期刊论文

Dosimetric impacts of dose grid resolution on stereotactic body radiotherapy for non-small-cell lung cancer

中文

中国医学物理学杂志

1005-202X

2019

36

1

6-11

10.3969/j.issn.1005-202X.2019.01.002

国家重点研发计划（2017YFC0113200）；

本校为第一机构

目的:定量分析剂量网格分辨率的大小对非小细胞肺癌(NSCLC)立体定向放射治疗(SBRT)计划剂量分布的影响,指导临床选用合适的剂量网格分辨率用于肺癌SBRT计划设计。方法:选取10例NSCLC患者,采用容积旋转调强技术,使用0.20 cm的剂量网格分辨率设计SBRT计划,将治疗计划结果再分别用0.40、0.30、0.25、0.15、0.10 cm的剂量网格分辨率计算最终剂量。比较6种不同剂量网格分辨率下的计划靶区(PTV):D2%、D_(mean)、D98%、均匀性指数(HI)、适形度指数(CI)和危及器官:全肺、胸壁、食管、心脏、脊髓、主动脉、气管树等的相关剂量学参数的差异。结果:与0.20 cm剂量网格分辨率组计划相比较,0.40、0.30、0.25、...

Objective To quantitatively analyze the effects of dose grid resolution on the dose distribution of stereotactic body radiotherapy (SBRT) of non-small-cell lung cancer (NSCLC) for providing guidance in selecting the optimal dose grid resolution for the design of SBRT plan of lung cancer. Methods Ten patients with NSCLC were enrolled in this study. With 0.20 cm dose grid resolution, volumetric modulated arc therapy technology was used to design SBRT plan, and then the dose grid resolution was set to 0.40, 0.30, 0.25, 0.15, 0.10 cm to calculate the final dose. Several dosimetric parameters of pl...