期刊论文

中文

中国医学物理学杂志

1005-202X

2018

35

5

503-508

10.3969/j.issn.1005-202X.2018.05.002

国家自然科学基金

本校为其他机构

目的:研究基于形变配准技术评估心脏及左心室肌剂量-体积指标的可行性。方法:回顾性分析21例患者屏气下心电门控四维CT(4DCT),在4DCT的20个时相(0%、5%......95%)上分别勾画心脏、左心室肌。使用商用软件MIM Maestro(MIM)中的基于密度的自由形变算法,将最小体积和以0%时相为参照的最小相似性指数(DSC)时相的心脏、左心室肌分别形变到最大体积和DSC时相上,并参照其形变场对剂量进行相应的形变。分析形变前后心脏及左心室肌相对于最大体积/DSC时相的体积、平均剂量(D_(mean))、V_(20)、V_(30)及V_(40)等参数的变化。结果:将最小体积时相的心脏形变到最大体积时相,形变前后的体积与最大体积的差由(...

Objective To discuss the feasibility of applying deformable image registration for assessing dose-volume parameters and the dosimetry parameters of the heart and the left ventricular myocardium (LVM). Methods The electrocardiogram-gate fourdimensional CT images of 21 patients were analyzed retrospectively. The heart and LVM were delineated on 20 phases of 4DCT images (0%, 5%, ⋯, 95%). With the use of intensity-based free-form deformable registration algorithm of MIM Maestro, the heart and LVM in minimum volume and minimum dice similarity coeff...