期刊论文

Successive multi-fractionated autoplanning for nasopharyngeal carcinoma based on the first fractionated objective function

中文

中国医学物理学杂志

1005-202X

2018

35

12

1386-1391

10.3969/j.issn.1005-202X.2018.12.004

福建省自然科学基金(2015Y0010) 福建省卫生计生中青年骨干人才培养项目(2017-ZQN-15).

本校为第一机构

目的:利用Perl语言编写Pinnacle计划系统脚本的嵌入式自动化程序,进行多分次鼻咽癌调强治疗计划快速自动设计,研究多分次自动计划设计的可行性及设计效率。方法:选取14例鼻咽癌患者,每例患者均在整个治疗过程中接受4次CT模拟图像(分别为CT1、CT2、CT3、CT4)。在Pinnacle计划系统(9.2m版本)上基于首次CT模拟图像(CT1)手工设计出满足处方剂量和危及器官剂量限制要求的调强放疗计划,并将CT1上手工计划的目标函数设置参数用Perl语言写入Pinnacle计划系统脚本,应用于同一患者的后续3个分次间CT图像(CT2、CT3、CT4)的自动计划设计。同时,由工作经验分别为不足1年和大于5年的两位物理师基于CT2独立设计...

Objective To evaluate the feasibility and efficiency of multi-fractionated autoplanning on nasopharyngeal carcinoma (NPC) with Perl-based scripts in Pinnacle treatment planning system. Methods A total of 14 NPC patients were selected, and 4 sets of simulated CT images (CT1, CT2, CT3 and CT4) for each patient were derived during the treatment. Each radiotherapy plan on its first set of simulated CT images (CT1) was manually created according to the prescribed dose to target areas and dose constraints to organs-at-risk on Pinnacle treatment plann...