期刊论文

Effect of jaw-setting in volumetric modulated arc therapy for cervical cancer

中文

中国医学物理学杂志

1005-202X

2016

33

10

1002-1007

10.3969/j.issn.1005-202X.2016.10.006

本校为第一机构

研究宫颈癌容积旋转调强技术(VMAT)中铅门设置对靶区的均匀性(HI)、适形度(CI)、机器跳数(MU)及危及器官受量的影响,从而得出针对宫颈癌VMAT设计的最优方案。方法:釆用Eclipse TPS(8.6)系统中VMAT对随机抽取的12例宫颈癌患者用3种铅门设置方法进行计划设计,分别为:固定铅门在15 cm宽度(x1、x2方向铅门与射野中心距离基本相等,因宫颈癌靶区较大,靶区两侧边缘包绕不全,铅门横向方向大小为15cm),称为2ARC计划;铅门固定在包绕靶区(两个全弧的x1、x2方向都完全包绕其方向靶区,铅门横向距离大于15 cm)位置进行计划优化,称为MAX计划;固定铅门在15 cm(x方向,第一个全弧arc1中x1方向能够完全包绕此方向靶...

Objective To design the optimal volumetric modulated arc therapy (VMAT) plan for cervical cancer by studying on the effect of jaw-setting on the homogeneity index (HI), conformity index (CI), monitor unit (MU) and dose of organs at risk (OAR). Methods Totally, 12 patients with cervical cancer were randomly selected, and Eclipse TPS 8.6 system was used to design VMAT plan for the selected patient. The plan resulted with three different jaw- setting ways, including 2ARC plan, MAX plan, and HALF plan. In 2ARC plan, the jaw was set at the 15 cm in the direction of x (the distance of x1 to beam cen...