Circulating CXCR3(+) Tfh cells positively correlate with neutralizing antibody responses in HCV-infected patients

首页 > 成果 > 详情

认领

导出

下载 Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhang, Jian;Liu, Wenpei;Wen, Bo;Xie, Ting;Tang, Ping;...

通讯作者：

Qu, Xiaowang

作者机构：

[Xie, Ting; Liu, Ziyan; Tang, Ping; Zhang, Jian; Huang, Liyan; Hu, Yabin; Jin, Kun; Wen, Bo; Qu, Xiaowang; Liu, Wenpei; Zhang, Ping; Niu, Ling] Univ South China, Peoples Hosp Chenzhou 1, Translat Med Inst, Chenzhou 423000, Hunan, Peoples R China.

[Qu, Xiaowang; Liu, Wenpei] Southern Med Univ, Affiliated Peoples Hosp Chenzhou 1, Chenzhou 423000, Hunan, Peoples R China.

通讯机构：

[Qu, Xiaowang] U

[Qu, Xiaowang] S

Univ South China, Peoples Hosp Chenzhou 1, Translat Med Inst, Chenzhou 423000, Hunan, Peoples R China.

Southern Med Univ, Affiliated Peoples Hosp Chenzhou 1, Chenzhou 423000, Hunan, Peoples R China.

语种：

英文

期刊：

Scientific Reports

ISSN：

2045-2322

年：

2019

卷：

期：

DOI：

10.1038/s41598-019-46533-w

基金类别：

Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81471959, 81501746]; Clinical Medical Innovation Technology Guide Project of Hunan Province [2018SK5030, 2018SK50304, 2018SK50308]; Science Foundation of XiangNan University [2017XJ53]

机构署名：

本校为第一且通讯机构

院系归属：

医学院

摘要：

Circulating T follicular helper (cTfh) cells have been identified as counterparts of germinal center Tfh (GC Tfh) cells in humans and can support T-dependent B cell maturation and antibody production in vitro. However, the role of cTfh cells in neutralizing antibody (nAb) responses in HCV infection remains unclear. Here, we characterized the phenotype and function of cTfh cells and demonstrated the associations of cTfh cells and their subsets with nAb responses in HCV infection. A total of 38 HCV-infected individuals and 28 healthy controls wer...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Circulating CXCR3(+) Tfh cells positively correlate with neutralizing antibody responses in HCV-infected patients

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问