Urinary metabolomics reveals novel interactions between metal exposure and amino acid metabolic stress during pregnancy

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成果类型：

期刊论文

作者：

Wang, Mu;Xia, Wei;Liu, Hongbin;Liu, Fang;Li, Han;...

通讯作者：

Xu, Shunqing;Lu, Songfeng

作者机构：

[Xia, Wei; Li, Yuanyuan; Li, Han; Xu, Shunqing; Wang, Mu; Pan, Xinyun; Liu, Hongxiu; Sun, Xiaojie; Chang, Huailong; Wu, Chuansha; Liu, Wenyu; Jiang, Yangqian] Huazhong Univ Sci & Technol, Minist Educ, Sch Publ Hlth, Key Lab Environm & Hlth,Tongji Med Coll, Wuhan, Hubei, Peoples R China.

[Xia, Wei; Li, Yuanyuan; Li, Han; Xu, Shunqing; Wang, Mu; Pan, Xinyun; Liu, Hongxiu; Sun, Xiaojie; Chang, Huailong; Wu, Chuansha; Liu, Wenyu; Jiang, Yangqian] Huazhong Univ Sci & Technol, Minist Environm Protect, Sch Publ Hlth, Tongji Med Coll, Wuhan, Hubei, Peoples R China.

[Xia, Wei; Li, Yuanyuan; Li, Han; Xu, Shunqing; Wang, Mu; Pan, Xinyun; Liu, Hongxiu; Sun, Xiaojie; Chang, Huailong; Wu, Chuansha; Liu, Wenyu; Jiang, Yangqian] Huazhong Univ Sci & Technol, State Key Lab Environm Hlth Incubat, Sch Publ Hlth, Tongji Med Coll, Wuhan, Hubei, Peoples R China.

[Wang, Mu; Sun, Jie; Liu, Fang; Lu, Songfeng] Huazhong Univ Sci & Technol, Sch Comp Sci & Technol, Wuhan, Hubei, Peoples R China.

[Liu, Hongbin] Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Zool, Wuhan, Hubei, Peoples R China.

通讯机构：

[Xu, Shunqing; Lu, Songfeng] H

Huazhong Univ Sci & Technol, Minist Educ, Sch Publ Hlth, Key Lab Environm & Hlth,Tongji Med Coll, Wuhan, Hubei, Peoples R China.

Huazhong Univ Sci & Technol, Minist Environm Protect, Sch Publ Hlth, Tongji Med Coll, Wuhan, Hubei, Peoples R China.

Huazhong Univ Sci & Technol, State Key Lab Environm Hlth Incubat, Sch Publ Hlth, Tongji Med Coll, Wuhan, Hubei, Peoples R China.

Huazhong Univ Sci & Technol, Sch Comp Sci & Technol, Wuhan, Hubei, Peoples R China.

语种：

英文

期刊：

TOXICOLOGY RESEARCH

ISSN：

2045-452X

年：

2018

卷：

期：

页码：

1164-1172

DOI：

10.1039/c8tx00042e

机构署名：

本校为其他机构

院系归属：

公共卫生学院

摘要：

Pregnant women are a unique group undergoing profound structural modifications in uterus, breast, adipose tissue and extracellular fluids. Amino acid metabolic stress is a unique physical process that occurs during pregnancy. Metals constitute a fundamental part of the maternal body and have a universal effect on amino acid metabolism. However, the exact interaction between metals and amino acid metabolism during pregnancy is unknown. The aim of the present study was to determine the correlations of metals with amino acid metabolic intermediate...

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Urinary metabolomics reveals novel interactions between metal exposure and amino acid metabolic stress during pregnancy

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