The ERK1/2 pathway participates in the upregulation of the expression of mesenteric artery α1 receptors by intravenous tail injections of mmLDL in mice

首页 > 成果 > 详情

认领

导出

下载 Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Wang, Jun-Jie;Chen, Xiao-Lan;Xu, Cang-Bao;Jiang, Gao-Feng;Lin, Jie;...

通讯作者：

Li, Jie

作者机构：

[Chen, Xiao-Lan; Li, Jie; Lin, Jie; Wang, Jun-Jie] Xiangnan Univ, Peoples Hosp Chenzhou 1, Chenzhou 423000, Hunan, Peoples R China.

[Li, Jie; Jiang, Gao-Feng; Qin, Xu-Ping] Univ South China, Inst Pharm & Pharmacol, Hengyang, Hunan, Peoples R China.

[Xu, Cang-Bao] Xian Med Univ, Inst Basic & Translat Med, Xian, Peoples R China.

[Liu, En-Qi] Xi An Jiao Tong Univ, Sch Med, Lab Anim Ctr, Xian 710049, Peoples R China.

通讯机构：

[Li, Jie] X

Xiangnan Univ, Peoples Hosp Chenzhou 1, Chenzhou 423000, Hunan, Peoples R China.

语种：

英文

关键词：

5-hydroxytryptamine (PubChem CID: 5202);Acetylcholine (PubChem CID: 6060);Extracellular signal-regulated kinase type 1/2;IL-1beta;Mesenteric artery;Minimally modified low density lipoprotein;Noradrenaline (PubChem CID: 439,260);Prazosin (PubChem CID: 68,546);Rauwolscine (PubChem CID: 197,067);TNF-alpha;U0126 (PubChem CID: 3,006,531);alpha(1) adrenoceptor

期刊：

Vascular Pharmacology

ISSN：

1537-1891

年：

2016

卷：

页码：

80-88

DOI：

10.1016/j.vph.2015.09.007

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81202535]; Education Department of Hu'nan Province [15K114, 12B117]; Science and Technology Bureau of Chenzhou, Hunan Province, China [CZ2014015]

机构署名：

本校为其他机构

院系归属：

药学与生物科学学院

摘要：

Minimally modified low density lipoprotein (mmLDL) is a risk factor for cardiovascular diseases. However, no studies examining the effect of mmLDL on vascular smooth muscle receptors have been released. The current study investigated the effect of mmLDL on the mesenteric artery at adrenoceptor and the molecular mechanisms. Mice were divided into the normal saline (NS), mmLDL, and mmLDL + U0126 groups. In the mmLDL + U0126 group, the animals were subjected to an intravenous tail injection of mmLDL and an intraperitoneal injection of U0126. Vascular tension caused by noradrenaline (NA) in mesent...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

The ERK1/2 pathway participates in the upregulation of the expression of mesenteric artery α1 receptors by intravenous tail injections of mmLDL in mice

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问