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Comprehensive Genomic Characterization of Campylobacter Genus Reveals Some Underlying Mechanisms for its Genomic Diversification

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成果类型:
期刊论文
作者:
Zhou, Yizhuang;Bu, Lijing;Guo, Min;Zhou, Chengran;Wang, Yongdong;...
通讯作者:
Chen, Liyu
作者机构:
[Zhou, Yizhuang; Guo, Min] BGI Shenzhen, Shenzhen, Guangdong, Peoples R China.
[Bu, Lijing] Univ New Mexico, Dept Biol, Albuquerque, NM 87131 USA.
[Zhou, Chengran] Sichuan Univ, Dept Biol, Chengdu 610064, Sichuan Provinc, Peoples R China.
[Wang, Yongdong] Univ South China, Key Discipline Lab Natl Def Biotechnol Uranium Mi, Hengyang, Hunan, Peoples R China.
[Chen, Liyu] Cent South Univ, Xiangya Sch Med, Dept Microbiol, Changsha, Hunan, Peoples R China.
通讯机构:
[Chen, Liyu] C
Cent South Univ, Xiangya Sch Med, Dept Microbiol, Changsha, Hunan, Peoples R China.
语种:
英文
关键词:
Campylobacter;Genomics;Phylogenetic analysis;Ribosomal RNA;Paleogenetics;Bacterial genomics;Sequence alignment;Viral genomics
期刊:
PLOS ONE
ISSN:
1932-6203
年:
2013
卷:
8
期:
8
页码:
e70241
基金类别:
Natural Science Foundation of Hunan Province, ChinaNatural Science Foundation of Hunan Province [10JJ2012]
机构署名:
本校为其他机构
院系归属:
核资源工程学院
摘要:
Campylobacter species.are phenotypically diverse in many aspects including host habitats and pathogenicities, which demands comprehensive characterization of the entire Campylobacter genus to study their underlying genetic diversification. Up to now, 34 Campylobacter strains have been sequenced and published in public databases, providing good opportunity to systemically analyze their genomic diversities. In this study, we first conducted genomic characterization, which includes genome-wide alignments, pan-genome analysis, and phylogenetic iden...

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