This work was supported by the Natural Science Foundation of Hunan Province (Grant No. 2021JJ40455), the Projects of the Hunan Health Committee (Grant No. 202112071537), the National Innovation and Entrepreneurship Training program for college students (Grant No. 202110555102), the Innovation and Entrepreneurship Training program for college students of the University of South China (Grant Nos. X202010555371 and X202010555372), and Graduate Student Research Innovation Project of Hunan Province (Grant No. CX20221007).