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Genetic Diversity of Mycobacterium tuberculosis Isolates from Inner Mongolia, China

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成果类型:
期刊论文
作者:
Yu, Qin;Su, Yunkai;Lu, Bing;Ma, Yan;Zhao, Xiuqin;...
通讯作者:
Wan, Kanglin
作者机构:
[Zhao, Xiuqin; Wan, Li; Lu, Bing; Yu, Qin; Lian, Lulu; Wan, Kanglin; Dong, Haiyan] Chinese Ctr Dis Control & Prevention, Natl Inst Communicable Dis Control & Prevent, State Key Lab Infect Dis Prevent & Control, Beijing, Peoples R China.
[Wu, Yimou; Yu, Qin; Lian, Lulu; Wan, Kanglin] Univ South China, Pathogen Biol Inst, Hengyang, Hunan, Peoples R China.
[Liu, Yao; Su, Yunkai; Yang, Xiaomin; Ma, Yan] Inner Mongolia Inst TB Control & Prevent, Hohhot, Peoples R China.
通讯机构:
[Wan, Kanglin] C
Chinese Ctr Dis Control & Prevention, Natl Inst Communicable Dis Control & Prevent, State Key Lab Infect Dis Prevent & Control, Beijing, Peoples R China.
语种:
英文
关键词:
Mycobacterium tuberculosis;China;Tuberculosis;Genotyping;Polymerase chain reaction;Molecular epidemiology;Tandem repeats;Fungal genetics
期刊:
PLOS ONE
ISSN:
1932-6203
年:
2013
卷:
8
期:
5
页码:
e57660
基金类别:
project "Transmission Mode of Tuberculosis'' of the National Key Program of Mega Infectious Disease [2008ZX100/03-010-02]; project of the State Key Laboratory for Infectious Disease Prevention and Control [2011SKLID208]
机构署名:
本校为其他机构
院系归属:
医学院
摘要:
Background: Tuberculosis (TB) is a serious public health problem in China, and within China, Inner Mongolia has a high prevalence area of TB. Though studies on the genetic diversity of Mycobacterium tuberculosis (MTB) have been reported in many provinces, there are no such studies to date in Inner Mongolia. In this study, we investigated the genetic diversity of MTB in Inner Mongolia. Methodology/Principal Findings: In this study, we analyzed 372 clinical MTB isolates with 22-loci mycobacterial interspersed repetitive unit and variable-number tandem repeats (MIRU-VNTR), spoligotyping, large se...

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