Lower creatinine to cystatin C ratio is associated with an increased risk of MASLD: A cross-sectional and prospective study of 368,634 UK Biobank participants

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成果类型：

期刊论文

作者：

Wang, Jiaren;Zeng, Lin;Hong, Chang;Cui, Hao;Wang, Weizhen;...

通讯作者：

Zhu, H;Liu, L;Xiao, LS

作者机构：

[Liu, Li; He, Jingzhe; Wang, Jiaren; Li, Ruining; Li, Qimei; Zeng, Lin; Xiao, Lushan; Li, Yan; Hong, Chang; Cui, Hao] Southern Med Univ, Nanfang Hosp, Hepatol Unit, Guangdong Prov Key Lab Viral Hepatitis Res, Guangzhou, Peoples R China.

[Liu, Li; He, Jingzhe; Wang, Jiaren; Li, Ruining; Li, Qimei; Zeng, Lin; Xiao, Lushan; Li, Yan; Hong, Chang; Cui, Hao] Southern Med Univ, Nanfang Hosp, Dept Infect Dis, Guangzhou, Peoples R China.

[Liu, Li; Wang, Jiaren; Xiao, Lushan] Southern Med Univ, Nanfang Hosp, Big Data Ctr, Guangzhou, Peoples R China.

[Wang, Weizhen] Southern Med Univ, Nanfang Hosp, Dept Ultrasound, Guangzhou, Peoples R China.

[Zhu, Hongbo] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Med Oncol, Hengyang, Hunan, Peoples R China.

通讯机构：

[Xiao, LS ; Liu, L ; Zhu, H ] S

Southern Med Univ, Nanfang Hosp, Guangzhou 510515, Peoples R China.

Southern Med Univ, Nanfang Hosp, Big Data Ctr, Guangzhou 510515, Peoples R China.

Southern Med Univ, Nanfang Hosp, Hepatol Unit, Guangdong Prov Key Lab Viral Hepatitis Res, Guangzhou 510515, Peoples R China.

Southern Med Univ, Nanfang Hosp, Dept Infect Dis, Guangzhou 510515, Peoples R China.

语种：

英文

关键词：

CCR;MSFLD;risk factor;UK Biobank

期刊：

Clinical Endocrinology

ISSN：

0300-0664

年：

2024

卷：

100

期：

页码：

116-123

DOI：

10.1111/cen.14990

基金类别：

National Natural Science Foundation of China [2020YFC2006400]; National Key R&D Program of China [81972897, 82172751]; National Nature Science Foundation of China [202201011183]; Guangzhou Science and Technology Project [2022A1515110656]; Guangdong Basic and Applied Basic Research Foundation [S202312121118, 92668]; Guangdong Province College Students' Innovative Entrepreneurial Training Progarm

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

OBJECTIVE: Metabolic dysfunction-associated steatotic liver disease (MASLD) affects many populations, and screening out the high-risk populations at an early stage is a challenge. As a sarcopenia index, the relationship between creatinine to cystatin C ratio (CCR) and MASLD remains unclear. This cross-sectional, prospective study aimed to explore the relationship between CCR and MASLD. Design Firstly, explored the correlation between CCR and MASLD in cross-sectional analyses. Then excluded the population with baseeline diagnosis of MASLD and an...

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Lower creatinine to cystatin C ratio is associated with an increased risk of MASLD: A cross-sectional and prospective study of 368,634 UK Biobank participants

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