Main differential endometrial microbiota associated with recurrent implantation failure: a case control study

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成果类型：

期刊论文

作者：

Gao, Hong*;Xiao, Jing;Liang, Bingyan;Wang, Xiaolan;Li, Huanhuan;...

通讯作者：

Gao, Hong;Wu, BY;Gao, H

作者机构：

[Gao, Hong; Wu, Baoyu] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Nursing, Hengyang, Hunan, Peoples R China.

[Gao, Hong] Ottawa Hosp, Res Inst, Ottawa, ON, Canada.

[Liang, Bingyan; Xiao, Jing] Univ South China, Sch Nursing, Hengyang, Hunan, Peoples R China.

[Li, Genlin; Wang, Xiaolan] Univ South China, Affiliated Hosp 1, Ctr Combinat Obstet & Gynecol & Reprod Med, Hengyang Med Sch, Hengyang, Hunan, Peoples R China.

[Li, Huanhuan] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Gynecol, Hengyang, Hunan, Peoples R China.

通讯机构：

[Gao, H ] O

[Wu, BY ; Gao, H] U

Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Nursing, Hengyang, Hunan, Peoples R China.

Ottawa Hosp, Res Inst, Ottawa, ON, Canada.

语种：

英文

关键词：

16S ribosomal RNA gene sequencing;endometrial microbiota;endometrial tissue;major differential microorganisms;recurrent implantation failure

期刊：

FRONTIERS IN ENDOCRINOLOGY

ISSN：

1664-2392

年：

2025

卷：

页码：

1504609

DOI：

10.3389/fendo.2025.1504609

基金类别：

China Scholarship Council [202008430075]; Ottawa Hospital Research Institute-Taggart-Parkes Foundation

机构署名：

本校为第一且通讯机构

院系归属：

护理学院

摘要：

INTRODUCTION: Recurrent implantation failure (RIF) is a major challenge in reproductive medicine, and emerging evidence suggests that alterations in the endometrial microbiota may play a critical role in its pathogenesis. To identify the main differential endometrial microbiota associated with RIF and to establish threshold values for their relative abundance. METHODS: This case-control study was conducted in the Departments of Obstetrics, Gynecology, and Reproductive Medicine at two large hospitals. From March to December 2023, the study recruited 17 infertile patients with RIF (Group A, case...

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Main differential endometrial microbiota associated with recurrent implantation failure: a case control study

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