期刊论文

中文

中国临床药理学与治疗学

1009-2501

2022

27

6

632-638

10.12092/j.issn.1009-2501.2022.06.005

:湖南省分子靶标新药研究协同创新项目 2010XQD44:南华大学归国人员基金资助项目 0223-0002-00031:南华大学研究生创新项目 2022jh042693:衡阳市指导性科技计划项目 ZK2021-05:湖南环境生物职业技术学院青年基金项目

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AIM:To study the protective effect and mechanism of swimming on kidney of diabetic mice.METHODS:The mice were randomly divided into normal control group,normal swimming group,type 2 diabetes mellitus(T2 DM)mice model group,diabetic swimming group and metformin group.T2 DM model was established by streptozotocin(STZ)method.The mice in normal swimming group and diabetic swimming group were given swimming exercise(1 h a day),and the metformin group were given metformin(200 mg/kg)by gavage once a day for 7 weeks.Fasting blood glucose and serum insulin were measured and insulin resistance index was...