Sodium alginate hydrogelation mediated paper-based POCT sensor for visual distance reading and smartphone-assisted colorimetric dual-signal determination of L-lactate - 成果

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Sodium alginate hydrogelation mediated paper-based POCT sensor for visual distance reading and smartphone-assisted colorimetric dual-signal determination of _L-lactate

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Wang, Wenjuan;Chen, Danrong;Cai, Yujiao;Liu, Zijing;Yang, Hongfen;...

通讯作者：

Yang, SY

作者机构：

[Liu, Zijing; Yang, Shengyuan; Cai, Yujiao; Yang, Hongfen; Liu, Jinquan; Wang, Wenjuan; Chen, Danrong; Yang, SY] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Dept Publ Hlth Lab Sci, Hengyang 421001, Hunan, Peoples R China.

[Liu, Zijing; Yang, Shengyuan; Cai, Yujiao; Yang, Hongfen; Liu, Jinquan; Wang, Wenjuan; Chen, Danrong; Yang, SY] Univ South China, Hunan Key Lab Typ Environm Pollut & Hlth Hazards, Hengyang 421001, Hunan, Peoples R China.

[Xie, Hongbin] Hengyang Ctr Dis Control & Prevent, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Yang, SY ] U

Univ South China, Sch Publ Hlth, Hengyang Med Sch, Dept Publ Hlth Lab Sci, Hengyang 421001, Hunan, Peoples R China.

Univ South China, Hunan Key Lab Typ Environm Pollut & Hlth Hazards, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

期刊：

ANALYTICAL METHODS

ISSN：

1759-9660

年：

2024

卷：

期：

页码：

2077-2084

DOI：

10.1039/d4ay00041b

基金类别：

National Natural Science Foundation of China [82073604]; National Natural Science Foundation of China [S202310555042]; National Training Program of Innovation and Entrepreneurship for Undergraduates

机构署名：

本校为第一且通讯机构

院系归属：

公共卫生学院

摘要：

Herein, we present a paper-based POCT sensor based on lactate dehydrogenase-mediated alginate gelation combined with visual distance reading and smartphone-assisted colorimetric dual-signal analysis to determine the concentration of (L)-lactate in yogurt samples. In this research, (L)-lactate was transformed into pyruvate by lactate dehydrogenase. Pyruvate then triggered the gelation of a sol mixture, increasing the viscosity (eta(s)) of the mixture, which was shown as a decrease in the diffusion diameter on the paper-based sensor. In addition, protons from pyruvate accelerated the degradation...

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Sodium alginate hydrogelation mediated paper-based POCT sensor for visual distance reading and smartphone-assisted colorimetric dual-signal determination of _L-lactate

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