版权说明 操作指南
首页 > 成果 > 详情

A novel computational model for predicting potential LncRNA-disease associations based on both direct and indirect features of LncRNA-disease pairs

认领
导出
下载 Link by 万方学术期刊
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Xiao, Yubin;Xiao, Zheng;Feng, Xiang;Chen, Zhiping;Kuang, Linai;...
通讯作者:
Wang, Lei
作者机构:
[Feng, Xiang; Chen, Zhiping; Wang, Lei; Xiao, Yubin] Changsha Univ, Coll Comp Engn & Appl Math, Changsha 410001, Peoples R China.
[Xiao, Zheng] Univ South China, Canc Res Inst, Hunan Prov Key Lab Tumor Cellular & Mol Pathol, Hengyang 421001, Hunan, Peoples R China.
[Kuang, Linai; Wang, Lei; Xiao, Yubin] Xiangtan Univ, Key Lab Hunan Prov Internet Things & Informat Sec, Xiangtan 411105, Peoples R China.
通讯机构:
[Wang, Lei] C
[Wang, Lei] X
Changsha Univ, Coll Comp Engn & Appl Math, Changsha 410001, Peoples R China.
Xiangtan Univ, Key Lab Hunan Prov Internet Things & Informat Sec, Xiangtan 411105, Peoples R China.
语种:
英文
关键词:
LncRNA-disease association prediction;Features;Random walk;Multiple linear regression;Artificial neural network
期刊:
BMC Bioinformatics
ISSN:
1471-2105
年:
2020
卷:
21
期:
1
页码:
1-22
基金类别:
This research was partly sponsored by the National Natural Science Foundation of China (No. 61873221, No. 61672447) and the Natural Science Foundation of Hunan Province (No. 2018JJ4058, No. 2019JJ70010, No. 2017JJ5036). Publication costs were funded by the National Natural Science Foundation of China (No. 61873221, No. 61672447). The funder of manuscript is Lei Wang (L.W.), whose contribution are stated in the section of Author’s Contributions. The funding body has not played any roles in the design of the study and collection, analysis and interpretation of data in writing the manuscript.
机构署名:
本校为其他机构
院系归属:
医学院
摘要:
Background: Accumulating evidence has demonstrated that long non-coding RNAs (lncRNAs) are closely associated with human diseases, and it is useful for the diagnosis and treatment of diseases to get the relationships between lncRNAs and diseases. Due to the high costs and time complexity of traditional bio-experiments, in recent years, more and more computational methods have been proposed by researchers to infer potential lncRNA-disease associations. However, there exist all kinds of limitations in these state-of-the-art prediction methods as ...

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com