期刊论文

Zheng, K;Xie, QH

英文

Microbial Pathogenesis

0882-4010

2023

184

106374

10.1016/j.micpath.2023.106374

CRediT authorship contribution statement Tang Jun: Resources, Formal analysis, Data curation. Liu Zhimin: Methodology, Investigation, Data curation. Deng Xi: Validation, Software, Resources. Wu Hua: Project administration, Methodology, Investigation. Shen Huilong: Visualization, Validation, Supervision. Peng Jiaofeng: Formal analysis, Data curation, Conceptualization. Zheng Kang: Writing – original draft, acquisition. Qinghua Xie: Writing – original draft, Software.

本校为通讯机构

Treponema pallidum (T. pallidum), an obligate extracellular bacterium, is the causative agent of sexually transmitted bacterial diseases. In this study, the glycolytic enzyme enolase (Tp Eno) of T. pallidum were injected intramuscularly into C57BL/6 mice, resulting in higher levels of specific anti-Tp Eno antibodies and Tp Eno-specific splenocyte proliferation than those in the mice immunized with recombinant protein Tp Eno. Cytokine (IL-4, IL-6, IL-10, IFN-γ, and TNF-α) analysis of splenocytes showed that the Tp Eno could slightly trigger th...