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Circular RNA: A new expectation for cardiovascular diseases

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成果类型:
期刊论文
作者:
Xie, Qiao;Ma, Yun;Ren, Zhong;Gu, Tianhe;Jiang, Zhisheng
通讯作者:
Ma, Y
作者机构:
[Xie, Qiao; Ma, Yun; Gu, Tianhe] Univ South China, Inst Biochem & Mol Biol, Hengyang Med Coll, Hengyang 421001, Hunan, Peoples R China.
[Ma, Yun] Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dru, Hengyang Med Sch, Hengyang, Hunan, Peoples R China.
[Ren, Zhong; Jiang, Zhisheng; Ma, Yun] Univ South China, Hengyang Med Sch, Hunan Int Sci & Technol Cooperat Base Arterioscler, Inst Cardiovasc Dis,Key Lab Arteriosclerol Hunan P, Hengyang, Hunan, Peoples R China.
通讯机构:
[Ma, Y ] U
Univ South China, Inst Biochem & Mol Biol, Hengyang Med Coll, Hengyang 421001, Hunan, Peoples R China.
语种:
英文
关键词:
biological marker;circular ribonucleic acid;microRNA;circular ribonucleic acid;aging;atherosclerosis;biogenesis;bioinformatics;cardiac aging;cardiovascular disease;diabetic cardiomyopathy;direct back splicing;exon skipping;gene control;gene function;gene interaction;genetic code;genetic transcription;heart failure;heart hypertrophy;heart infarction;heart muscle fibrosis;human;medical research;nonhuman;pathogenesis;pulmonary hypertension;Review;RNA splicing;ventricular hypertrophy;atherosclerosis;bioinformatics;cardiovascular disease;conserved sequence;controlled study;diabetic cardiomyopathy;heart failure;heart hypertrophy;heart infarction;heart muscle fibrosis;prevalence;pulmonary hypertension;review;tissue specificity
期刊:
JOURNAL OF CELLULAR BIOCHEMISTRY
ISSN:
0730-2312
年:
2023
卷:
125
期:
2
页码:
e30512
基金类别:
This work was supported by the National Key Research and Development Project (2019YFA0801601) and the National Natural Science Foundation of China (81971087).
机构署名:
本校为第一且通讯机构
院系归属:
医学院
药学与生物科学学院
摘要:
Circular RNA (circRNA) is a class of RNA with the 5' and 3' ends connected covalently to form a closed loop structure and characterized by high stability, conserved sequences and tissue specificity, which is caused by special reverse splicing methods. Currently, it has become a hot spot for research. With the discovery of its powerful regulatory functions and roles, the molecular mechanisms and future value of circRNA in participating in and regulating biological and pathological processes are becoming increasingly apparent. Among them is the i...

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