期刊论文

中文

中华性传播感染杂志：英文版

1608-6260

2004

4

1

28-31

Financially supported by a grant from the Education Com-mittee of Hunan Province （No.ooAoo9）；

本校为第一机构

目的为了解人型支原体和解脲支原体对氟喹诺酮类药物的敏感性,指导临床合理用药。方法采用微量肉汤稀释法测定了人型支原体和解脲支原体对 6 种氟喹诺酮类药物的敏感性。结果司帕沙星和加替沙星对人型支原体和解脲支原体具有良好的活性,其 MIC50S 分别为 0.03125、0.25μg/ml 和 0.25、0.5μg/ml。左氧氟沙星和氧氟沙星对两种支原体的 MIC50S 均分别为 1μg/ml和 2μg/ml。诺氟沙星对两种支原体的活性较差,MIC50S 分别为 16μg/ml 和 32μg/ml。环丙沙星对人型支原体的 MIC50S 为 2μg/ml,而对解脲支原体的MIC50S 则为 8μg/ml。结论本研究结果为选择氟喹诺酮类药物来治疗泌尿生殖道支原体感染提...

Objectives: To determine the susceptibilities of M.hominis and U. urealyticum to fluoroquinolones for the instruction of reasonable clinical application of antibiotics.Method: The susceptibilities of M. hominis and U.urealyticum to six fluoroquinolones were determined by the broth dilution method.Results: Sparfloxacin and gatifloxacin were very active with MIC50S of 0.03125 and 0.25 μg/ml against M. hominis, 0.25 and 0.5 μg/ml against U. urealyticum,respectively. Levofloxacin and ofloxacin had MIC50S of 1 μg/ml and 2 μg/ml, respectively aga...