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Association between sarcopenia‐related markers and cholelithiasis: A prospective and Mendelian randomization study

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成果类型:
期刊论文
作者:
Ma, Pengcheng;Li, Ruining;Zeng, Lin;Hong, Chang;Li, Yan;...
通讯作者:
Xu, J;Liu, Li;Xiao, LS
作者机构:
[Ma, Pengcheng; Liang, Shengxing; Xu, Jun] Southern Med Univ, Sch Publ Hlth, Guangzhou, Peoples R China.
[Ma, Pengcheng; Li, Zeyang; Xu, Jun] Southern Med Univ, Sch Hlth Management, Guangzhou, Peoples R China.
[Ma, Pengcheng; Xu, Jun] Southern Med Univ, Nanfang Hosp, Guangzhou, Peoples R China.
[Liu, Li; He, Jingzhe; Wang, Jiaren; Li, Ruining; Zeng, Lin; Xiao, Lushan; Li, Yan; Hong, Chang; Cui, Hao] Southern Med Univ, Nanfang Hosp, Hepatol Unit, Guangdong Prov Key Lab Viral Hepatitis Res, Guangzhou, Peoples R China.
[Liu, Li; He, Jingzhe; Wang, Jiaren; Li, Ruining; Zeng, Lin; Xiao, Lushan; Li, Yan; Hong, Chang; Cui, Hao] Southern Med Univ, Nanfang Hosp, Dept Infect Dis, Guangzhou, Peoples R China.
通讯机构:
[Xiao, LS ; Xu, J ; Liu, L] S
Southern Med Univ, Nanfang Hosp, Guangzhou 510515, Peoples R China.
Southern Med Univ, Nanfang Hosp, Hepatol Unit, Guangdong Prov Key Lab Viral Hepatitis Res, Guangzhou 510515, Peoples R China.
Southern Med Univ, Nanfang Hosp, Dept Infect Dis, Guangzhou 510515, Peoples R China.
语种:
英文
关键词:
Mendelian randomization;cholelithiasis;hand grip strength;sarcopenia;skeletal muscle index;walking pace
期刊:
ENVIRONMENTAL TOXICOLOGY
ISSN:
1520-4081
年:
2024
基金类别:
Guangdong Natural Science Foundation [92668]
机构署名:
本校为其他机构
院系归属:
医学院
摘要:
Cholelithiasis is a common digestive disease that drives a myriad of adverse complications. The correlation between sarcopenia and various digestive disorders has been extensively researched, whereas its association with cholelithiasis remains unreported. We aimed to investigate the association through prospective and Mendelian randomization (MR) analyses and establish a quantitative score reflecting the impact of sarcopenia-related markers on cholelithiasis. The prospective study involved 448 627 participants from the UK Biobank. Cox proporti...

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