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The potential value of microRNA-4463 in the prognosis evaluation in hepatocellular carcinoma

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成果类型:
期刊论文
作者:
Hu, Tian;Li, Jincheng;Zhang, Chuhong;Lv, Xiu;Li, Sai;...
通讯作者:
Wen, Meiling;Zuo, Jianhong
作者机构:
[Tan, Yixi; Zuo, Jianhong; Lv, Xiu; Wen, Meiling; Zhang, Chuhong; Li, Sai; Yan, Hanxing; Hu, Tian; He, Sha] Univ South China, Affiliated Nanhua Hosp, Hengyang 421001, Hunan, Peoples R China.
[Zuo, Jianhong; Hu, Tian] Univ South China, Sch Med, Hengyang 421001, Hunan, Peoples R China.
[Li, Jincheng] Shaoyang Univ, Med Sch, Shaoyang 422000, Hunan, Peoples R China.
[Lei, Mingsheng] Zhangjiajie City Hosp, Dept Resp & Crit Care Med, Zhangjiajie 427000, Hunan, Peoples R China.
通讯机构:
[Wen, Meiling; Zuo, Jianhong] U
Univ South China, Affiliated Nanhua Hosp, Hengyang 421001, Hunan, Peoples R China.
Univ South China, Sch Med, Hengyang 421001, Hunan, Peoples R China.
语种:
英文
关键词:
Hepatocellular carcinoma;malignant tumors;microRNA-4463;microRNA-6087;miR-4463;Prognostic
期刊:
基因与疾病
ISSN:
2352-4820
年:
2017
卷:
4
期:
2
页码:
116-122
基金类别:
Grantsponsor: National Nature Science Foundation of China, Grant number: 81272960; Key Research Program from Science and TechnologyDepartment of Hunan Province China, Grant number: 2013WK2010 and 2014SK2015; Key Research Program from Ministry of human Resources and Social Security of the People's Republic of China, Grant number: (2016)176; The fund of Tianqing liver disease research, Grant number: (TQGB20140155).
机构署名:
本校为第一且通讯机构
院系归属:
医学院
摘要:
The purpose of this study is to measure the expression of microRNA-4463 and microRNA-6087 between normal persons and patients with hepatocellular carcinoma (HCC), and to clarify the meaning of them in the prognosis evaluation in HCC. Forty-five samples from healthy people and patients, who had been diagnosed with hepatocellular carcinoma before any treatment, were collected to study respectively. Real-time PCR was used to detect the expression of miRNA-4463 and miRNA-6087 in the serum of control group and hepatocellular carcinoma patients. The ...

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