The role of hormones in ILC2-driven allergic airway inflammation

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成果类型：

期刊论文

作者：

Dai, Zhongling;Gong, Zhande;Wang, Cui;Long, WeiXiang;Liu, Duo;...

通讯作者：

Lei, AH;Zhang, HJ

作者机构：

[Long, WeiXiang; Lei, AH; Lei, Aihua; Dai, Zhongling; Liu, Duo; Gong, Zhande; Wang, Cui] Univ South China, Inst Pathogen Biol, Sch Basic Med Sci, Hengyang Med Sch, 28 Changsheng Western Rd, Hengyang 421001, Hunan, Peoples R China.

[Long, WeiXiang; Lei, Aihua; Dai, Zhongling; Liu, Duo; Gong, Zhande; Wang, Cui] Univ South China, Hunan Prov Key Lab Special Pathogens Prevent & Con, Hengyang, Peoples R China.

[Long, WeiXiang; Lei, Aihua; Dai, Zhongling; Liu, Duo; Gong, Zhande; Wang, Cui] Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dru, Hengyang, Peoples R China.

[Zhang, Haijun] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Cardiol, 69 Chuanshan Ave, Hengyang 421000, Hunan, Peoples R China.

通讯机构：

[Lei, AH ; Zhang, HJ ] U

Univ South China, Inst Pathogen Biol, Sch Basic Med Sci, Hengyang Med Sch, 28 Changsheng Western Rd, Hengyang 421001, Hunan, Peoples R China.

Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Cardiol, 69 Chuanshan Ave, Hengyang 421000, Hunan, Peoples R China.

语种：

英文

关键词：

allergic airway inflammation;hormones;ILC2s

期刊：

Scandinavian Journal of Immunology

ISSN：

0300-9475

年：

2024

卷：

期：

页码：

e13357-

DOI：

10.1111/sji.13357

基金类别：

the Natural Science Foundation of Hunan Province [2022JJ20034, 2022JJ50165]; Natural Science Foundation of Hunan Province [22B0412]; Research Foundation of the Hunan Provincial Education Bureau [202202074638]; Research Foundation of Health Commission of Hunan Province [S202210555231, S202210555235]; Hunan Provincial College Students' innovation and Entrepreneurship Training Program

机构署名：

本校为第一且通讯机构

院系归属：

医学院

摘要：

Group 2 innate lymphoid cells (ILC2s) are a type of innate immune cells that produce a large amount of IL-5 and IL-13 and two cytokines that are crucial for various processes such as allergic airway inflammation, tissue repair and tissue homeostasis. It is known that damaged epithelial-derived alarmins, such as IL-33, IL-25 and thymic stromal lymphopoietin (TSLP), are the predominant ILC2 activators that mediate the production of type 2 cytokines. In recent years, abundant studies have found that many factors can regulate ILC2 development and function. Hormones synthesized by the body's endocr...

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The role of hormones in ILC2-driven allergic airway inflammation

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