Background: Radiotherapy, a primary approach in cancer treatment, damages normal cells while targeting cancer cells. Therefore, it is crucial to identify drugs with minimal side effects, high reliability, and radioprotective effects to develop novel radiotherapy strategies. Hemerocallis citrina extracts (HCE), which are derived from plants with medicinal and culinary applications, possess antioxidative and anticancer properties. Methods: In this study, we investigated the radioprotective effects of HCE on LO2 cells exposed to radiation to determine whether these effects were mediated through t...