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Cell membrane-camouflaged nanoparticles as drug carriers for cancer therapy

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成果类型:
期刊论文
作者:
Xu, Cheng-Hui;Ye, Peng-Ju;Zhou, Yang-Chun;He, Dong-Xiu;Wei, Hua*;...
通讯作者:
Wei, Hua;Yu, Cui-Yun
作者机构:
[Xu, Cheng-Hui; Wei, Hua; Zhou, Yang-Chun; Ye, Peng-Ju; He, Dong-Xiu; Wei, H; Yu, Cui-Yun] Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang 421001, Peoples R China.
[Xu, Cheng-Hui; Wei, Hua; Zhou, Yang-Chun; Ye, Peng-Ju; He, Dong-Xiu; Yu, Cui-Yun] Univ South China, Inst Pharm Pharmacol, Sch Pharmaceut Sci, Hengyang 421001, Peoples R China.
通讯机构:
[Wei, H; Yu, CY] U
Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
Biomimetic nanoparticle;Cancer therapy;Cell membrane;Drug delivery;Nanomedicine
期刊:
Acta Biomaterialia
ISSN:
1742-7061
年:
2020
卷:
105
页码:
1-14
基金类别:
The authors deeply acknowledge the sponsorship from the Outstanding Youth Fund of Natural Science Foundation of Hunan province ( 2017JJ1024 ), National Natural Science Foundation of China ( 81471777 ), the Health Department of Hunan Province 225 Talent Project to Cui-Yun Yu and the Chuanshan Talent Program of the University of South China to Cui-Yun Yu ( 2017-43 ).
机构署名:
本校为第一且通讯机构
院系归属:
药学与生物科学学院
摘要:
The translocation of natural cell membranes to the surface of synthetic nanoparticles, which allows man-made vectors to share merits and functionalities created by nature, has been a hot subject of research in the past decade. The resulting biomimetic nanoparticles not only retain the physicochemical properties of nanomaterials, but also inherit the advantageous functions of source cells. Combined with the preponderances of both synthetic and natural platforms, the optimized biomimetic systems can maximize the drug delivery efficiency. In this ...

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