This work was supported by grants from the National Nature Science Foundation China (No. 30070870) and the National Major Basic Research Program of China (No. G2000056905).
机构署名：
本校为其他机构
院系归属：
药学与生物科学学院
摘要：
The present study was designed to examine the effect of calcitonin gene-related peptide (CGRP) on angiotensin II-induced proliferation of cultured rat vascular smooth muscle cells. Vascular smooth muscle cells were grown from explants of Sprague-Dawley rat aorta. Vascular smooth muscle cells (between passages 5 and 10) were incubated with 0.1% neonatal calf serum for 48 h, and then treated with angiotensin II (100 nM) in the absence or presence of CGRP for 24 h. The viability, DNA synthesis and cell cycle of vascular smooth muscle cells were me...
