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In vitro activities of erythromycin, Tetracycline and levofloxacin alone and in dual combinations against ureaplasma spp.

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成果类型:
期刊论文
作者:
Luo, Di-Qing*;Liu, Jing-Ye;Yang, Wei;Zhang, Bin;Yu, Min-Jun;...
通讯作者:
Luo, Di-Qing
作者机构:
[Luo, Di-Qing; Zhang, Bin; Liu, Jing-Ye] Sun Yat Sen Univ, Affiliated Hosp 1, Huangpu Hosp, Dept Dermatol, Guangzhou 510700, Guangdong, Peoples R China.
[Yang, Wei] Sun Yat Sen Univ, Affiliated Hosp 1, Huangpu Hosp, Dept Pharm, Guangzhou 510700, Guangdong, Peoples R China.
[Yu, Min-Jun; Wu, Yi-Mou] Nanhua Univ, Coll Med, Pathogenic Biol Inst, Hengyang, Peoples R China.
[Luo, Di-Qing] Sun Yat Sen Univ, Affiliated Hosp 1, Huangpu Hosp, Dept Dermatol, 183 Huangpu Rd E, Guangzhou 510700, Guangdong, Peoples R China.
通讯机构:
[Luo, Di-Qing] S
Sun Yat Sen Univ, Affiliated Hosp 1, Huangpu Hosp, Dept Dermatol, 183 Huangpu Rd E, Guangzhou 510700, Guangdong, Peoples R China.
语种:
英文
关键词:
Antimicrobial agents;Erythromycin;Tetracycline;Levofloxacin;Ureaplasma spp.
期刊:
CHEMOTHERAPY
ISSN:
0009-3157
年:
2011
卷:
57
期:
2
页码:
128-133
基金类别:
Guangdong Provincial Natural Science Foundation, ChinaNational Natural Science Foundation of Guangdong Province [07001677]
机构署名:
本校为其他机构
院系归属:
医学院
摘要:
Purpose: It was the aim of our study to evaluate the in vitro activities of tetracycline (TET), erythromycin (ERY) and levofloxacin (LVX) alone and in dual combinations against ureaplasmas. Methods: The minimum inhibitory concentrations (MICs) of 51 ureaplasmal strains were determined by microdilution assay. Results: TET was the most active when the antibiotics were used alone. The combinations resulted in significantly decreased MICs for every agent compared with the use of single antibiotics (p < 0.05, respectively), except for ERY in the ERY...

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