期刊论文

Jiang, Zhi-Sheng

英文

CURRENT MEDICINAL CHEMISTRY

0929-8673

2021

28

1

152-168

10.2174/0929867327666200306124418

The work has been supported by the National Natural Science Foundation of China (91839103, 81670429, 81470435 to ZS.Jiang), International Joint Laboratory for Arteriosclerotic Disease Research of Hunan Province (2018WK4031), “Double First-Class” project for innovative Group of Basic Medicine, University of South China (to ZS.Jiang).

本校为第一且通讯机构

Atherosclerosis is a chronic inflammatory vascular disease. Atherosclerotic cardiovascular disease is the main cause of death in both developed and developing countries. Many pathophysiological factors, including abnormal cholesterol metabolism, vascular inflammatory response, endothelial dysfunction and vascular smooth muscle cell proliferation and apoptosis, contribute to the development of atherosclerosis and the molecular mechanisms underlying the development of atherosclerosis are not fully understood. Ubiquitination is a multistep post-translational protein modification that participates...