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Macrophage polarization in atherosclerosis

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成果类型:
期刊论文
作者:
Yang, Sai;Yuan, Hou-Qin;Hao, Ya-Meng;Ren, Zhong;Qu, Shun-Lin;...
通讯作者:
Jiang, Zhi-Sheng
作者机构:
[Jiang, Zhi-Sheng; Hao, Ya-Meng; Ren, Zhong; Tang, Zhi-Han; Qu, Shun-Lin; Yuan, Hou-Qin; Wei, Dang-Heng; Yang, Sai; Liu, Lu-Shan] Univ South China, Inst Cardiovasc Dis, Key Lab Arteriosclerosis Hunan Prov, Hengyang City 421001, Hunan, Peoples R China.
[Zhang, Ji-Feng] Univ Michigan, Frankel Cardiovasc Ctr, Dept Internal Med, 2800 Plymouth Rd NCRC Bldg26-3575, Ann Arbor, MI 48109 USA.
通讯机构:
[Jiang, Zhi-Sheng] U
Univ South China, Inst Cardiovasc Dis, Key Lab Arteriosclerosis Hunan Prov, Hengyang City 421001, Hunan, Peoples R China.
语种:
英文
关键词:
Atherosclerosis;Macrophage polarization;Phenotype
期刊:
Clinica Chimica Acta
ISSN:
0009-8981
年:
2020
卷:
501
页码:
142-146
基金类别:
This work was supported by the National Natural Science Foundation of China , China ( 81670429 , 81470435 , to ZSJ), “Double First-Class” project for innovative Group of Basic Medicine, University of South China , China (to ZSJ) and International Joint Laboratory for Arteriosclerotic Disease Research of Hunan Province , China ( 2018WK4031 ).
机构署名:
本校为第一且通讯机构
院系归属:
医学院
摘要:
Atherosclerosis is a chronic inflammatory response that increases the risk of cardiovascular diseases. An in-depth study of the pathogenesis of atherosclerosis is critical for the treatment of atherosclerotic cardiovascular disease. The development of atherosclerosis involves many cells, such as endothelial cells, vascular smooth muscle cells, macrophages, and others. The considerable effects of macrophages in atherosclerosis are inextricably linked to macrophage polarization and the resulting phenotype. Moreover, the significant impact of macrophages on atherosclerosis depend not only on the ...

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