[ Objective ] To explore the protective effect and mechanism of metallothionein to mice testis damaged by nickel and chromium. [Methods] The mice testis injury model induced by nickel and chromium was injected different dose metallothionein into abdomen for consecutive 7 days, once a day and 0.1 mL/10 g body weight. All mice were sacrificed in the 36th day. The testicular organ coefficient, sperm quantity, vivi-sperm rate, malformation rate and the testicular tissue morphous changes were observed. The concentration of SOD and MDA and the activi...
