Study on the Therapeutic Effects of Bisdemethoxycurcumin on a Cerebral Amyloid Angiopathy Mouse Model Established via Chronic Treatment With Five Vascular Risk Factors

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Lin, Shudong;Zhu, Guanghua;Xie, Juan;Wen, Xuanwei;Deng, Limin;...

通讯作者：

Xiao, ZJ

作者机构：

[Deng, Limin; Lin, Shudong; Xie, Juan; Chen, Shuangxi; Liu, Guozhi; Xiao, Zijian; Wen, Xuanwei; Li, Sijing; Zhu, Guanghua; Wang, Feiyan; Xiao, ZJ] Univ South China, Affiliated Hosp 1, Multi Res Ctr Brain Disorders, Hengyang Med Sch,Dept Neurol, Hengyang, Hunan, Peoples R China.

[Deng, Limin; Lin, Shudong; Chen, Shuangxi; Liu, Guozhi; Xiao, Zijian; Wen, Xuanwei; Li, Sijing; Zhu, Guanghua; Wang, Feiyan; Xiao, ZJ] Univ South China, Clin Res Ctr Immune Related Encephalopathy Hunan P, Hengyang Med Sch, Hengyang, Hunan, Peoples R China.

[Xie, Juan] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Emergency, Hengyang, Hunan, Peoples R China.

通讯机构：

[Xiao, ZJ ] U

Univ South China, Affiliated Hosp 1, Multi Res Ctr Brain Disorders, Hengyang Med Sch,Dept Neurol, Hengyang, Hunan, Peoples R China.

Univ South China, Clin Res Ctr Immune Related Encephalopathy Hunan P, Hengyang Med Sch, Hengyang, Hunan, Peoples R China.

语种：

英文

关键词：

cerebral amyloid angiopathy (CAA);curcumin;learning and memory;necroptosis;neuroinflammation

期刊：

Brain and Behavior

ISSN：

2162-3279

年：

2025

卷：

期：

页码：

e70245-

DOI：

10.1002/brb3.70245

基金类别：

National Key Clinical Specialty Scientific Research Project, Grant/Award Number:Z2023067; the Key Scientific Research Project of Hunan Provincial Department of Education, Grant/Award Number:22A0314 [22A0314]; Key Scientific Research Project of Hunan Provincial Department of Education [20230383]; National Key Clinical Specialties Major Scientific Research Projects

机构署名：

本校为第一且通讯机构

院系归属：

医学院

摘要：

BACKGROUND AND PURPOSE: Cerebral amyloid angiopathy (CAA) is recognized as a major contributor to progressive cognitive decline and cerebral hemorrhages in the elderly population. Currently, there is a global shortage of safe and effective treatments for this condition. Bisdemethoxycurcumin (BDMC) has been demonstrated to exhibit pharmacological effects with anti-Aβ toxicity properties. Thus, the present study mainly focused on the potential therapeutic effects of BDMC on CAA. METHOD: The 30 male C57BL/6 mice were subjected to chronic treatmen...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Study on the Therapeutic Effects of Bisdemethoxycurcumin on a Cerebral Amyloid Angiopathy Mouse Model Established via Chronic Treatment With Five Vascular Risk Factors

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问