期刊论文

Zhang, Xingang

英文

ACS CATALYSIS

2155-5435

2019

9

9

8224-8229

10.1021/acscatal.9b02488

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21425208, 21672238, 21790362, 21421002]; Strategic Priority Research Program of the Chinese Academy of SciencesChinese Academy of Sciences [XDB20000000]; SIOC

本校为其他机构

Nickel-catalyzed carbodifunctionalization of alkenes is an efficient strategy for the construction of C-C bonds. However, applications of the strategy in dialkylation of alkenes remain underdeveloped due to the difficulties in suppressing competitive side reactions. We now describe a nickel-catalyzed tandem reaction by difluoroalkylation-alkylation of N-vinyl 2-pyrrolidinone with difluoroalkyl bromides and dialkylzinc reagents. The reaction can also extend to N-vinyloxazolidinone and N-vinylacetamide. This carbodifunctionalization reaction proc...