This study investigated the physiological thermal response of people under simulated weightlessness using a 6 degrees head down bed rest (HDBR) model to ensure the human body functions in the weightlessness way. Thermal responses of six male participants were experimentally determined. The relationship between thermal comfort and heart rate variability (HRV) was also scrutinized. Physiological responses of participants under different environmental conditions were observed including core temperature, sweating, and most importantly, HRV. Elevated core temperatures were observed amongst particip...