Identification of Ferroptosis Biomarker in AHH-1 Lymphocytes Associated with Low Dose Radiation

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成果类型：

期刊论文

作者：

Yin, Jie;Hu, Nan;Yi, Lan;Zhao, Weichao;Cheng, Xinjie;...

作者机构：

[Ding, Dexin; Yin, Jie; Yi, Lan; Li, Guangyue; Hu, Nan; Cheng, Xinjie; Zhao, Weichao] Univ South China, Key Discipline Lab Natl Def Biotechnol Uranium Mi, Hengyang 421001, Hunan, Peoples R China.

[Yin, Jie; Yi, Lan; Li, Guoqing; Yang, Nanyang] Univ South China, Coll Pharm & Biol Sci, Hengyang 421001, Hunan, Peoples R China.

[Yin, Jie; Yi, Lan; Li, Guoqing; Yang, Nanyang] Univ South China, Key Lab Ecol Environm & Crit Human Dis Prevent Hu, Dept Educ, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

accidents, nuclear, biological indicators, dose, low, health effects

期刊：

HEALTH PHYSICS

ISSN：

0017-9078

年：

2021

卷：

120

期：

页码：

541-551

DOI：

10.1097/HP.0000000000001385

基金类别：

Defense Industrial Technology Development Program [JCKY2016403C001]; Key Project of National Defense Basic Research [B3720132001]; Hunan Provincial Educational Department Foundation [14C0998]; Hunan Provincial Graduate Innovative Foundation [CX2015B386]

机构署名：

本校为第一机构

院系归属：

核资源工程学院

药学与生物科学学院

摘要：

The impact of long-term low-dose radiation on human health has always been a concern. Long-term low-dose gamma radiation causes cells continuous injury and causes chromosomal mutations to greatly increase the chance of cancer. Because it is significant to identify biomarkers for long-term low-dose gamma radiation, we investigate the influence of low dose rate on the gene expressions in the AHH-1 lymphocytes cell line (AHH-1 cells) for long-term irradiation. Different dose rates (7, 14, 26, 34, and 43 μGy h-1) of irradiation from gamma radiatio...

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Identification of Ferroptosis Biomarker in AHH-1 Lymphocytes Associated with Low Dose Radiation

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