Changsha Central Hospital Affiliated to University of South China Foundation of key Program#&#&#YNKY202205
Scientific Research Fund of Hunan Provincial Education Department#&#A0320
Hunan Provincial Natural Science Foundation of China#&#ߥJJ30753
机构署名：
本校为第一且通讯机构
院系归属：
药学与生物科学学院
摘要：
BACKGROUND: Potassium bismuth citrate is a gastric mucosal protector and a key drug for treating peptic ulcers. OBJECTIVE: To evaluate the pharmacokinetic characteristics and safety of 120-mg bismuth potassium citrate formulations administered orally under fasting conditions in healthy Chinese subjects. METHOD: A single-center open two-cycle trial was conducted on 12 healthy subjects who received a single oral dose of 120 mg of bismuth potassium citrate. The plasma concentration of bismuth was determined using a validated inductively coupled pl...
