Conceptualization, Y.L.; methodology, Y.-N.L., P.Z., W.-F.Y., C.-Y.Z. and Y.-L.Y.; validation, Y.L., Y.-N.L. and Y.-L.Y.; formal analysis, Y.-N.L., P.Z., W.-F.Y., C.-Y.Z. and Y.-L.Y.; investigation, P.Z., W.-F.Y. and C.-Y.Z.; resources, Y.L.; writing—original draft preparation, Y.-N.L., P.Z., W.-F.Y., C.-Y.Z. and Y.-L.Y.; writing—review and editing, Y.L., Y.-N.L. and Y.-L.Y.; visualization, Y.-N.L., P.Z., W.-F.Y., C.-Y.Z. and Y.-L.Y.; supervision, Y.L.; project administration, Y.L.; funding acquisition, Y.L. All authors have read and agreed to the published version of the manuscript. This research was funded by the Natural Science Foundation of Hunan Province (No. 2021JJ30597), Scientific Research Projects of Health Commission of Hunan Province (No. 202113022002), and Hengyang Guided Science and Technology Project (No. 2020jh042809).