NIR-to-Vis Handheld Platforms for Detecting miRNA Level and Mutation Based on Sub-10 nm Sulfide Nanodots and HCR Amplification

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhu, Yanli;Wang, Jikai;Xie, Haitao;Liu, Hailing;Liu, Shuangquan;...

通讯作者：

Wang, JK

作者机构：

[Zhu, Yanli] Hunan Univ Technol & Business, Sch Resources & Environm, Changsha 410205, Hunan, Peoples R China.

[Liu, Shuangquan; Xie, Haitao] Univ South China, Hengyang Med Sch, Affiliated Hosp 1, Dept Clin Lab, Hengyang 421001, Hunan, Peoples R China.

[Liu, Hailing] Wuhan Univ, Renmin Hosp, Dept Resp & Crit Care Med, Wuhan 430060, Hubei, Peoples R China.

[Wang, Jikai; Mi, Pengbing; He, Suisui; Wang, JK; Sun, Yiyang; He, Dongxiu; Wang, Jun] Univ South China, Hengyang Med Sch, Inst Pharm & Pharmacol, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Wang, JK ] U

Univ South China, Hengyang Med Sch, Inst Pharm & Pharmacol, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

alkaline-earth sulfide nanomaterials;NIR-excited fluorescence;miRNA assay;mutant loci;single-nucleotide polymorphism

期刊：

ACS Applied Materials & Interfaces

ISSN：

1944-8244

年：

2022

卷：

期：

页码：

10212-10226

DOI：

10.1021/acsami.2c00689

基金类别：

The authors acknowledge Chujin Wang from the National University of Singapore for manuscript revision and Dr. Jiecan Zhou from the First Affiliated Hospital of University of South China for technical assistance. This work is financially supported by the Natural Science Foundation of Hunan Province, China (Grant Nos. 2021JJ40452, 2019JJ80035), the Scientific Research Project of Hunan Provincial Health Commission (Grant No. 202112062218), the Scientific Research Fund of Hunan Provincial Education Department (Grant No. 21C0474), and the Doctoral Scientific Research Foundation of the University of South China (Grant Nos. 200XQD042, 190XQD142).

机构署名：

本校为通讯机构

院系归属：

医学院

药学与生物科学学院

摘要：

Sub-10 nm monodisperse alkaline-earth sulfide nanodots (ASNDs) with bright near-infrared (NIR)-excitation fluorescence and adjustable emission wavelength were prepared by a thermal decomposition method for the first time. The ASNDs exhibited high NIR-to-vis conversion efficiency and served as multicolor fluorescent labels in the proposed miR-224 assay. Targeted detection of the miR-224 level and single-nucleotide variation in miR-224 was carried out on a smartphone-based platform using a hybridization chain reaction (HCR) amplification strategy...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

NIR-to-Vis Handheld Platforms for Detecting miRNA Level and Mutation Based on Sub-10 nm Sulfide Nanodots and HCR Amplification

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问