期刊论文

Shi, Jin-Feng;Mo, Zhong-Cheng

英文

DNA AND CELL BIOLOGY

1044-5498

2017

36

12

1142-1150

10.1089/dna.2017.3813

This study was supported by grants from the Natural Sciences Foundation of Hunan Province (No. 14JJ2084), College Students’ Research Learning and Innovative Experiment Plan in University of South China (No. 2017XJYZ051), the Zhengxiang Scholar (Xiangyang Tang) Program of the University of South China, and The Construct Program of the Key Discipline in Hunan Province (Basic Medicine Sciences at the University of South China).

本校为第一且通讯机构

Members of the reticulon protein family are predominantly distributed within the endoplasmic reticulum. The neurite outgrowth inhibitor (Nogo) has three subtypes, including Nogo-A (200 kDa), Nogo-B (55 kDa), and Nogo-C (25 kDa). Nogo-A and Nogo-C are potent Nogos that are predominantly expressed in the central nervous system. Nogo-B, the splice variant of reticulon-4, is expressed widely in multiple human organ systems, including the liver, lung, kidney, blood vessels, and inflammatory cells. Moreover, the Nogo-B receptor (NgBR) can interact wi...