期刊论文

First-line drugs resistance of Mycobacterium tuberculosis isolated from inpatients and its influencing factors in the four provinces of northwestern China

中文

中国人兽共患病学报

1002-2694

2017

33

5

398-402,422

10.3969/j.issn.1002-2694.2017.05.003

国家科技重大专项 Funded by the National Science and Technology Major Project of China

本校为第一机构

目的了解西北地区结核分枝杆菌耐药状况及其影响因素,为预防和控制耐药结核病提供基础科学依据。方法选取中国西北4省、自治区(甘肃、西藏、新疆、内蒙古)2005-2011年从结核病患者痰标本中分离培养的757株结核分枝杆菌(MTB),采用比例法检测MTB对4种一线抗结核药物链霉素(SM)、利福平(RFP)、异烟肼(INH)和乙胺丁醇(EMB)的敏感性,结合病例背景资料分析相关影响因素。结果共检测了757株结核分枝杆菌,对SM、RFP、INH和EMB的耐药率分别为28.14%、26.68%、26.02%和7.53%,总的耐药率和耐多药率分别为40.55%和18.63%。西藏、新疆、甘肃和内蒙古的总耐药率和MDR率分别为64.42%和42.94%、40.48%和23.81%、...

In this study, we investigated the status of the first-line drugs resistance （DR） of Mycobacterium tuberculosis （MTB） and its influencing factors in the four provinces of northwestern China to provide basic scientific evidence for the prevention and control of drug-resistant tuberculosis （TB）. A total of 757 clinical MTB isolates from the sputum specimens of the patients with TB in 2005-2011 from four provinces and the autonomous regions （Gansu, Tibet, Xinjiang, Inner Mongolia） of Northwest China were collected. The drug susceptibility ...