期刊论文

中文

中国人兽共患病学报

1002-2694

2017

33

4

300-304

10.3969/j.issn.1002-2694.2017.04.002

国家科技重大专项（No.2013ZX10003002-001）资助~~；

本校为第一机构

目的了解西南地区结核分枝杆菌临床分离株的耐药表型及其影响因素情况,为结核病的预防和控制提供基础参考数据。方法选取中国西南4个地区(贵州、广西、四川和重庆)2006—2013年从结核病患者痰标本中分离培养的500株结核分枝杆菌,用比例法药物敏感试验对4种一线抗结核药物进行药物敏感性检测,用SPSS22.0中的χ~2检验和Logistic回归进行统计学分析。结果500株结核分枝杆菌临床分离株,对INH、RFP、EMB和SM的耐药率分别为30.40%、26.00%、 9.80%和24.40%,总体耐药率和耐多药率分别是40.60%和27.20%;贵州、四川、广西和重庆的总耐药率和MDR率分别为64.10%和46.15%、59.54%和51.90%、28.88%和14.97%、...

The drug-resistance and its influencing factors of clinical isolates of Mycobacterium tuberculosis （M. tuberculosis） in Southwest China were investigated in this study, for providing the basic scientific reference for the prevention and control of tuberculosis （TB）. A total of 500 clinical isolates of M. tuberculosis from the sputum specimens of the patients with TB in 2006-2013 were collected in the four provinces of the southwestern China （Guizhou, Guangxi, Sichuan and Chongqing）. The drug susceptibility of the strains to the four drugs...