期刊论文

Jiang, Zhi-Sheng

英文

Cardiovascular Diabetology

1475-2840

2018

17

1

1-20

10.1186/s12933-018-0777-x

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81670429]; "Double First-Class" project for innovative Group of Basic Medicine, University of South China; NIHUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA [HL122664]; NATIONAL HEART, LUNG, AND BLOOD INSTITUTEUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Heart Lung & Blood Institute (NHLBI) [R01HL122664, R01HL122664, R01HL122664, R01HL122664, R01HL122664] Funding Source: NIH RePORTER

本校为第一且通讯机构

Perivascular adipose tissue (PVAT), the adipose tissue that surrounds most of the vasculature, has emerged as an active component of the blood vessel wall regulating vascular homeostasis and affecting the pathogenesis of atherosclerosis. Although PVAT characteristics resemble both brown and white adipose tissues, recent evidence suggests that PVAT develops from its own distinct precursors implying a closer link between PVAT and vascular system. Under physiological conditions, PVAT has potent anti-atherogenic properties mediated by its ability to secrete various biologically active factors that...