Repair of avascular meniscal injuries using juvenile meniscal fragments: An in vitro organ culture study

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成果类型：

期刊论文

作者：

Dai, Zhu;Li, Kanghua*;Chen, Zhiwei;Liao, Ying;Yang, Lezhong;...

通讯作者：

Li, Kanghua

作者机构：

[Li, Kanghua; Dai, Zhu] Cent S Univ, Xiangya Hosp, Dept Orthoped, Changsha 410078, Hunan, Peoples R China.

[Chen, Zhiwei; Dai, Zhu; Liu, Chunlei; Yang, Lezhong; Liao, Ying] South China Univ, Affiliated Hosp 1, Dept Orthoped, Hengyang 421001, Hunan, Peoples R China.

[Ding, Wenjun] South China Univ, Affiliated Hosp 1, Clin Res Inst, Hengyang 421001, Hunan, Peoples R China.

[Li, Kanghua] Cent S Univ, Xiangya Hosp, Dept Orthoped, 87 Xiangya Rd, Changsha 410078, Hunan, Peoples R China.

通讯机构：

[Li, Kanghua] C

Cent S Univ, Xiangya Hosp, Dept Orthoped, 87 Xiangya Rd, Changsha 410078, Hunan, Peoples R China.

语种：

英文

关键词：

in vitro;injury;integrative repair;meniscus;organ culture

期刊：

Journal of Orthopaedic Research

ISSN：

0736-0266

年：

2013

卷：

期：

页码：

1514-1519

DOI：

10.1002/jor.22405

基金类别：

Provincial Science and Technology Department of Hunan [2012SK3156]; Provincial Science Foundation of Hunan [10JJ3094]

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

We investigated whether the implantation of juvenile allograft and minced meniscal fragments could improve the healing of avascular meniscal injuries, which cannot heal spontaneously. Concentric cylindrical explants were excised from the inner two-thirds of swine medial menisci. The inner cylinder consisted of a "sandwich" structure, with minced juvenile meniscal fragments, juvenile meniscal columns, minced mature meniscal fragments, or mature meniscal columns implanted in the middle. The explants were cultured in vitro for 2, 4, or 6 weeks. Interfacial meniscal repair was assessed by histolog...

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Repair of avascular meniscal injuries using juvenile meniscal fragments: An in vitro organ culture study

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