Radiomics nomogram based on CT radiomics features and clinical factors for prediction of Ki-67 expression and prognosis in clear cell renal cell carcinoma: a two-center study

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Li, Ben;Zhu, Jie;Wang, Yanmei;Xu, Yuchao;Gao, Zhaisong;...

通讯作者：

Wang, Zhenguang;Yang, GJ

作者机构：

[Yang, Guangjie; Gao, Zhaisong; Wang, Zhenguang; Zhang, Ju; Zhuang, Yuan; Wang, ZG; Li, Ben] Qingdao Univ, Affiliated Hosp, Dept Nucl Med, 59 Haier Rd, Qingdao 266061, Shandong, Peoples R China.

[Li, Ben] Qingdao Univ, Sch Basic Med, Qingdao, Shandong, Peoples R China.

[Zhu, Jie] Qingdao Univ, Affiliated Hosp, Dept Sci Res Management & Foreign Affairs, Qingdao, Shandong, Peoples R China.

[Wang, Yanmei] GE Healthcare China, Shanghai, Peoples R China.

[Xu, Yuchao] Univ South China, Sch Nucl Sci & Technol, Hengyang, Hunan, Peoples R China.

通讯机构：

[Yang, GJ ; Wang, ZG] Q

Qingdao Univ, Affiliated Hosp, Dept Nucl Med, 59 Haier Rd, Qingdao 266061, Shandong, Peoples R China.

语种：

英文

关键词：

Clear cell renal cell carcinoma;Radiomics;Heterogeneity;Ki-67;Outcome

期刊：

CANCER IMAGING

ISSN：

1740-5025

年：

2024

卷：

期：

页码：

1-13

DOI：

10.1186/s40644-024-00744-1

基金类别：

Not applicable.

机构署名：

本校为其他机构

院系归属：

核科学技术学院

摘要：

To develop and validate a radiomics nomogram combining radiomics features and clinical factors for preoperative evaluation of Ki-67 expression status and prognostic prediction in clear cell renal cell carcinoma (ccRCC). Two medical centers of 185 ccRCC patients were included, and each of them formed a training group (n = 130) and a validation group (n = 55). The independent predictor of Ki-67 expression status was identified by univariate and multivariate regression, and radiomics features were extracted from the preoperative CT images. The...

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Radiomics nomogram based on CT radiomics features and clinical factors for prediction of Ki-67 expression and prognosis in clear cell renal cell carcinoma: a two-center study

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