The synthesis of α-amino acid from imines with different carbonyl sources is attractive for both synthetic organic and medicinal chemistry communities.Imines,which were easily available from the corresponding ketones and amines,were employed as one of the most ideal precursors.Traditionally,cyanation and subsequent hydrolysis were required to install the carboxyl group[1].In these cases,the toxicity of the cyanation reagents limited its further synthetic applications in organic chemsitry.Besides,metal activation of imine substrates to make the...
