CXCL2, a new critical factor and therapeutic target for cardiovascular diseases.

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Guo, Lin-Ya;Yang, Fang;Peng, Li-Jun;Li, Yan-Bing*;Wang, Ai-Ping*

通讯作者：

Wang, Ai-Ping;Li, Yan-Bing

作者机构：

[Wang, Ai-Ping; Guo, Lin-Ya] Univ South China, Inst Clin Med, Nanhua Affiliated Hosp, 336 Dongfeng Rd, Hengyang 421001, Hunan, Peoples R China.

[Wang, Ai-Ping; Li, Yan-Bing; Guo, Lin-Ya] Univ South China, Dept Anat, Sch Med, 28 Changsheng West Rd, Hengyang 421001, Hunan, Peoples R China.

[Yang, Fang] Univ South China, Inst Pharm & Pharmacol, Hengyang, Hunan, Peoples R China.

[Peng, Li-Jun] Univ South China, Pediat Acad, Med Record Stat Off & Lib, Changsha, Hunan, Peoples R China.

[Li, Yan-Bing] Southern Med Univ, Natl Key Discipline Human Anat, Guangdong, Guangdong, Peoples R China.

通讯机构：

[Wang, Ai-Ping; Li, Yan-Bing] U

Univ South China, Inst Clin Med, Nanhua Affiliated Hosp, 336 Dongfeng Rd, Hengyang 421001, Hunan, Peoples R China.

Univ South China, Dept Anat, Sch Med, 28 Changsheng West Rd, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

CXCL2;atherosclerosis;cardiovascular disease;inflammation

期刊：

Clinical and Experimental Hypertension

ISSN：

1064-1963

年：

2020

卷：

期：

页码：

428-437

DOI：

10.1080/10641963.2019.1693585

基金类别：

This project was financed by the National Natural Science Foundation of China [grand numbers 81600040 to AP Wang], the province Natural Science Foundation of Hu Nan [grand numbers 2017JJ3279 to AP Wang; 2017JJ3141 to LJ Peng], the Postdoctoral Science Fund of China [grant number 2017M622589 to AP Wang], Key Lab for Clinical Anatomy & Reproductive Medicine of Hengyang City (grand numbers 2017KJ182).

机构署名：

本校为第一且通讯机构

院系归属：

医学院

药学与生物科学学院

摘要：

Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Previous studies have shown that inflammatory chemokines are involved in the physiological functions of cytoskeletal reorganization, cell migration, adhesion and immune responses. However, in the past decade, there have been studies showing that inflammatory chemokines play a key role in CVD. Importantly, CXC motif chemokine ligand 2 (CXCL2) has been shown to be involved in the pathogenesis of cardiovascular disease. CXCL2 exerts its effects on the cardiovascular system by...

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CXCL2, a new critical factor and therapeutic target for cardiovascular diseases.

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