Vascular calcification is one sort of heterotopie calcification; it contains media calcification, which in turn relates to nephropathy, diabetes, and intima calcification which is associated with artherosclerosis. Vascular calcification is one of the many cardiovascular risk factors. Its presence is a strong indicator of chronic inflammatory disease. Atheroselerotic calcification may be one example of this process. Its extent directly shows a relationship with the overall burden of atherosclerotic disease, and has attracted a lot of attention. This article is a review of the progress made in r...