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Modulation of ferroptosis by non‑coding RNAs in cancers: Potential biomarkers for cancer diagnose and therapy

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成果类型:
期刊论文
作者:
Gong, Huifang;Li, Zheng;Wu, Zhimin;Lian, Gaojian*;Su, Zehong
通讯作者:
Lian, Gaojian;Su, ZH
作者机构:
[Li, Zheng; Lian, Gaojian; Su, Zehong; Gong, Huifang; Wu, Zhimin] Univ South China, Hengyang Med Sch, Dept Biochem & Mol Biol, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Lian, GJ; Su, ZH ] U
Univ South China, Hengyang Med Sch, Dept Biochem & Mol Biol, Hengyang 421001, Hunan, Peoples R China.
语种:
英文
关键词:
Biomarker;Cancer therapy;Ferroptosis;NcRNAs;Programmed cell death
期刊:
PATHOLOGY RESEARCH AND PRACTICE
ISSN:
0344-0338
年:
2024
卷:
253
页码:
155042
基金类别:
This work was supported by Hunan Provincial Natural Science Foundation of China (2023JJ50124) and Key Grand of Research and Development in Hunan Province (2023DK2005).
机构署名:
本校为第一且通讯机构
院系归属:
化学化工学院
药学与生物科学学院
摘要:
Ferroptosis is a recently discovered cell programmed death. Extensive researches have indicated that ferroptosis plays an essential role in tumorigenesis, development, migration and chemotherapy drugs resistance, which makes it become a new target for tumor therapy. Non-coding RNAs (ncRNAs) are considered to control a wide range of cellular processes by modulating gene expression. Recent studies have indicated that ncRNAs regulate the process of ferroptosis via various pathway to affect the development of cancer. However, the regulation network remains ambiguous. In this review, we outlined th...

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