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The role of ANXA1 in the tumor microenvironment

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成果类型:
期刊论文
作者:
Li, Lanxin;Wang, Baiqi;Zhao, Shuang;Xiong, Qinglin;Cheng, Ailan
通讯作者:
Ailan Cheng
作者机构:
[Li, Lanxin; Zhao, Shuang; Xiong, Qinglin] Hunan Engineering Research Center for Early Diagnosis and Treatment of Liver Cancer, Cancer Research Institute, Hengyang Medical School, University of South China, Hengyang, China
[Wang, Baiqi] The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, China
[Cheng, Ailan] Hunan Engineering Research Center for Early Diagnosis and Treatment of Liver Cancer, Cancer Research Institute, Hengyang Medical School, University of South China, Hengyang, China. Electronic address: 375355191@qq.com
通讯机构:
[Ailan Cheng] H
Hunan Engineering Research Center for Early Diagnosis and Treatment of Liver Cancer, Cancer Research Institute, Hengyang Medical School, University of South China, Hengyang, China
语种:
英文
关键词:
Angiogenesis;AnnexinA1;Immune;Inflammation;Tumor microenvironment
期刊:
International Immunopharmacology
ISSN:
1567-5769
年:
2024
卷:
131
页码:
111854
基金类别:
This work was supported by the National Natural Science Foundation of China (Grant No. 81072198 and No. 81372894), the Natural Science Foundation of Hunan Province (No. 2021JJ30589), and the Provincial Technological Innovation Guidance Project of Hunan Province (No. 2018SK51505).
机构署名:
本校为第一且通讯机构
院系归属:
医学院
摘要:
Annexin A1 (ANXA1) is widely expressed in a variety of body tissues and cells and is also involved in tumor development through multiple pathways. The invasion, metastasis, and immune escape of tumor cells depend on the interaction between tumor cells and their surrounding environment. Research shows that ANXA1 can act on a variety of cells in the tumor microenvironment (TME), and subsequently affect the proliferation, invasion and metastasis of tumors. This article describes the role of ANXA1 in the various components of the tumor microenvironment and its mechanism of action, as well as the e...

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