This work was aimed to investigate the effect of target genes of Wnt/β-catenin signaling pathway in human gastric MGC803 cells by overexpression of RORα. The proliferation of MGC803 cells was detected by MTT. The expressions of signal molecules in Wnt/β-catenin signaling pathway were tested by RT-PCR, Western blot and co-immunoprecipitation. Luciferase report gene assay was used to assess the promoter activity of c-Myc. MTT showed that the proliferation of MGC803 cells with overexpression of RORα was significantly attenuated compared with c...
