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Construction of robust fluorescent probe for CO detection and assessment of the efficacy of hyperbaric oxygen therapy acute CO poisoning

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成果类型:
期刊论文
作者:
Yang, Lin;Zhou, Liyi*;Yuan, Xiaomin;Pengxu, Lin;Liu, Ting;...
通讯作者:
Zhou, Liyi;Ren, JL;Chen, LZ
作者机构:
[Yang, Lin; Chen, Lizao] Univ South China, Affiliated Changsha Cent Hosp, Dept Hyperbar Oxygen, Changsha 410004, Hunan, Peoples R China.
[Pengxu, Lin; Zhou, Liyi; Zhou, LY; Ren, Jiali; Ren, JL; Yuan, Xiaomin; Liu, Ting] Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Hunan, Peoples R China.
通讯机构:
[Zhou, LY; Ren, JL ] C
[Chen, LZ ] U
Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Hunan, Peoples R China.
Univ South China, Affiliated Changsha Cent Hosp, Dept Hyperbar Oxygen, Changsha 410004, Hunan, Peoples R China.
语种:
英文
关键词:
Acute CO poisoning;Carbon monoxide;Gaseous signaling molecule;Hyperbaric oxygen therapy
期刊:
Journal of Hazardous Materials
ISSN:
0304-3894
年:
2025
卷:
484
页码:
136759
基金类别:
Natural Science Foundation of China (NSFC) [21605046]; Hunan Provincial Natural Science Foundation of China [2017JJ3060]
机构署名:
本校为第一且通讯机构
摘要:
Carbon monoxide (CO) is a colorless, odorless, toxic, and polluting gas produced by the incomplete combustion of carbon-containing substances such as coal and petroleum. CO is also a gaseous signaling molecule, which participates in and regulates a series of physiological and pathological processes. In this work, two kinds of CO-activated fluorescence probes 2 and 4 were designed and synthesized for the rapid detection of CO and evaluation of acute CO poisoning by hyperbaric oxygen therapy. Specifically, 2 and 4 both used the allyl formate group as the CO response unit and when they reacted wi...

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